Neuronal control of bodily function basic and clinical aspects vol 5 brain aging molecular biology the aging process and neurodegenerative disease neuronal control of bodily function basic and clinical aspects vol 5 brain aging molecular biology the aging process and neurodegenerative disease hugh c hendrie . Cellular senescence in brain aging and neurodegenerative diseases evidence and perspectives 1 department of biochemistry and molecular biology 2 department of pediatric and adolescent medicine and 3 department of cells with features of senescence have been detected in the context of brain aging and neurodegenerative disease . Molecular mechanisms of brain aging and neurodegenerative disorders lessons from dietary restriction the application of modern molecular and cell biology technologies to studies of the neurobiology of aging provides a window on the molecular substrates of successful brain aging and neurodegenerative disorders in rodents and humans . Aging is defined as a progressive time related accumulation of changes responsible for or at least involved in the increased susceptibility to disease and death the brain seems to be particularly sensitive to the aging process since the appearance of neurodegenerative diseases including alzheimers disease is exponential with the increasing age
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